Upsetting matter -- nag and scold (9)
I believe the answer is:
termagant
'scold' is the definition.
('termagant' can be a synonym of 'scold')
'upsetting matter nag' is the wordplay.
'upsetting' indicates anagramming the letters.
'matter'+'nag'='matternag'
'matternag' with letters rearranged gives 'TERMAGANT'.
'and' is the link.
(Other definitions for termagant that I've seen before include "Aggressive, overbearing woman" , "Scolding bad-tempered woman" , "Awful female" , "Nagging woman" , "Garment at odds with shrewish woman" .)