Urge lady of the house to scrap first two tablets (5)
I believe the answer is:
press
'urge' is the definition.
(I know that urge can be written as press)
'lady of the house to scrap first two tablets' is the wordplay.
I cannot really see how this works, but
'tablets' could be 'es' (E can refer to an ecstasy tablet) and 'es' is found within the answer.
'scrap first' could be 's' (1st letter of 'scrap') and 's' is found in the answer.
This may be the basis of the clue (or it may be nonsense).
(Other definitions for press that I've seen before include "Railroad" , "harass > crowd" , "needed to avoid crooked racket" , "Forcibly enlist" , "Weigh" .)