Used by those who have designs on others with skin problems (4)
I believe the answer is:
inks
'used by those who have designs on others' is the definition.
I can't tell whether this defines the answer.
'skin problems' is the wordplay.
'problems' indicates an anagram (I've seen 'problem' mean this).
'skin' is an anagram of 'INKS'.
'with' acts as a link.
Can you help me to learn more?
(Other definitions for inks that I've seen before include "Fluids from cuttlefish" , "Printers' mediums" , "Printers' media" , "Liquids used for printing" , "Printing fluids" .)