Using cane caused complaint (4)
I believe the answer is:
acne
'complaint' is the definition.
(acne is a kind of disease)
'using cane' is the wordplay.
'using' indicates an anagram.
'cane' with letters rearranged gives 'ACNE'.
'caused' acts as a link.
I am not very happy about this link. It may belong to another bit of the clue.
Can you help me to learn more?
(Other definitions for acne that I've seen before include "Youthful problem" , "Cane for the teenager?" , "Adolescent skin disease" , "Spotty skin condition" , "Problem to face in" .)