Uttered profanities, leaving wife angry (4)
I believe the answer is:
sore
'angry' is the definition.
(similar in meaning)
'uttered profanities leaving wife' is the wordplay.
'uttered profanities' becomes 'swore' (to swear is to utter profanities).
'leaving' suggests deleting specific letters.
'wife' becomes 'w'.
'swore' with 'w' taken out is 'SORE'.
(Other definitions for sore that I've seen before include "Painful or informally angry" , "To be very old" , "Aching; severe" , "Feeling pain or informally angry" , "Painful - resentful" .)