Crossword Genius

___ vaccine

Ross

I think it could be either:

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7

3*

antigen

(Other definitions for antigen that I've seen before include "Immunity-booster" , "Substance inducing an immune response" , "It stimulates immune responses - tag nine (anag)" , "Something inducing an immune response, neat gin (anag.)" , "toxin" .)

I've seen this clue in the Penny Press.
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