Vacuous blonde wife longed to be possessed (9)
I believe the answer is:
bewitched
'be possessed' is the definition.
(thesaurus)
'vacuous blonde wife longed' is the wordplay.
'vacuous' says to hollow out the word (remove centre letters).
'wife' becomes 'w' (abbreviation).
'longed' becomes 'itched' (I've seen this before).
'blonde' with its centre taken out is 'be'.
'be'+'w'+'itched'='BEWITCHED'
'to' is the link.
(Other definitions for bewitched that I've seen before include "Gripped" , "Under a spell" , "'''..., Bothered and Bewildered'' (Ella Fitzgerald song) (9)'" , "Charmed" , "seduced?" .)