Vagrant originally moved around in biblical land (5)
I believe the answer is:
nomad
'vagrant' is the definition.
(thesaurus)
'originally moved around in biblical land' is the wordplay.
'originally' indicates taking the first letters.
'in' indicates putting letters inside.
'biblical land' becomes 'Nod' (Cain was sent to the Land of Nod).
The initial letters of 'moved around' is 'ma'.
'ma' placed into 'nod' is 'NOMAD'.
(Other definitions for nomad that I've seen before include "Unsettled character" , "Rover" , "Unsettled type" , "being domestically unstable" , "Itinerant" .)