Valet in minister’s residence initially vilified in tirade (10)
I believe the answer is:
manservant
'valet' is the definition.
(a valet is a type of manservant)
'minister's residence initially vilified in tirade' is the wordplay.
'minister's residence' becomes 'manse' (house for a religious minister).
'initially' indicates taking the first letters.
'in' means one lot of letters goes inside another.
'tirade' becomes 'rant' (both can mean an angry outburst).
The initial letter of 'vilified' is 'v'.
'v' put within 'rant' is 'rvant'.
'manse'+'rvant'='MANSERVANT'
'in' acts as a link.
(Other definitions for manservant that I've seen before include "Valet" , "Chap's assistant" , "footman" .)