Variety of white wine first produced in the Rhine valley, now all over the world (8)
I believe the answer is:
riesling
(Other definitions for riesling that I've seen before include "Sir Ingle makes wine from this grape" , "Aromatic white wine from the Rhine valley" , "Dry white wine (German)" , "Gin riles the wine" , "Fragrant white wine from the Rhine valley or from California" .)