Very hot round West End area (4)
I believe the answer is:
'west end area' is the definition.
(I've seen this before)
'very hot round' is the wordplay.
'very' becomes 'so' (both can mean 'extremely').
'hot' becomes 'h' (abbreviation eg on taps).
'round' becomes 'o' (round can mean a round object).
'so'+'h'+'o'='SOHO'
(Other definitions for soho that I've seen before include "Parts of London and New York City with the same name" , "Colourful neighbourhood in London's West End" , "Once notorious part of central London" , "Huntsman's call - area of London" , "Entertainment district in London's West End" .)