Crossword Genius

Very large Mail cartoons reproduced (12)

Ross

I believe the answer is:

astronomical

'very large' is the definition.
(I've seen this before)

'mail cartoons reproduced' is the wordplay.
'reproduced' indicates anagramming the letters (I've seen 'reproduce' mean this).
'mail'+'cartoons'='mailcartoons'
'mailcartoons' is an anagram of 'ASTRONOMICAL'.

(Other definitions for astronomical that I've seen before include "Extremely large" , "Absolutely huge, in a heavenly way" , "Inconceivably large" , "Of the study of stars" , "Really, really big" .)

I've seen this clue in The Times.
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