Very significant couple caught hosting scam (6)
I believe the answer is:
iconic
'very significant' is the definition.
'couple caught hosting scam' is the wordplay.
'couple' becomes 'ii' (I've seen this in other clues).
'caught' becomes 'c' (cricket abbreviation).
'hosting' is an insertion indicator.
'scam' becomes 'con' (I've seen this before).
'ii'+'c'='iic'
'iic' enclosing 'con' is 'ICONIC'.
(Other definitions for iconic that I've seen before include "Well-known and representative of a particular idea" , "that's like an emoji?" , "of images" , "Highly representative" , "Worthy of veneration" .)