Vexatious English gang returned to squeeze different ones (10)
I believe the answer is:
'vexatious' is the definition.
'english gang returned to squeeze different ones' is the wordplay.
'english' becomes 'e' (abbreviation).
'gang' becomes 'mob' (synonyms).
'returned' says the letters should be written backwards.
'to squeeze' is an insertion indicator (inserted letters are squeezed inside).
'different ones' becomes 'others' (other people or things).
'emob' backwards is 'bome'.
'bome' placed around 'others' is 'BOTHERSOME'.
(Other definitions for bothersome that I've seen before include "causing trouble", "A pain", "Perplexing", "Annoying", "Trying".)