Victims of informal and formal neckwear items (10)
I believe the answer is:
casualties
'victims' is the definition.
(casualty is a kind of victim)
'informal and formal neckwear items' is the wordplay.
'informal' becomes 'casual' (similar in meaning).
'and' is a charade indicator (letters next to each other).
'formal neckwear items' becomes 'ties' (I am not sure about this - if you are sure you should believe this answer much more).
'casual'+'ties'='CASUALTIES'
'of' acts as a link.
Can you help me to learn more?
(Other definitions for casualties that I've seen before include "Injured people" , "Victims" .)