Villain in Broadmoor as callous (6)
I believe the answer is:
rascal
'villain' is the definition.
(rascal is a kind of villain)
'in broadmoor as callous' is the wordplay.
'in' indicates the answer is hidden within the clue.
'RASCAL' is hidden in the letters of 'broadmoor as callous'.
(Other definitions for rascal that I've seen before include "Mischievous person or confused lascar" , "Villain" , "Mischievous fellow" , "mischief-maker" , "Knave, rogue" .)