Crossword Genius

Villain's blemish (4)

Ross

I believe the answer is:

wart

(Other definitions for wart that I've seen before include "Disfiguring growth on skin" , "Horny skin growth" , "Verruca" , "Surgeon might remove it" , "Small hard viral skin blemish" .)

I've seen this clue in the King Feature Syndicate.
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