Vince in the lead? (5)
I believe the answer is:
cable
This clue is a double definition.
'vince' is the first definition.
(Sir Vince Cable)
'the lead?' is the second definition.
(thesaurus)
'in' acts as a link.
(Other definitions for cable that I've seen before include "Rope for communication" , "Hawser, wire" , "Wire, flex" , "Wire; message" , "This may pull car up" .)