Vindication of French miscreant (7)
I believe the answer is:
defence
'vindication' is the definition.
(I know that vindication can be written as defence)
'of french miscreant' is the wordplay.
'of french' becomes 'de' ('of' in French).
'miscreant' becomes 'fence' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'de'+'fence'='DEFENCE'
Can you help me to learn more?
(Other definitions for defence that I've seen before include "The D in MoD" , "A means of protecting from attack" , "Act of keeping safe from danger" , "Protection; justification" , "One ministry" .)