Virginia starts to languish and experience depression (4)
I believe the answer is:
vale
'depression' is the definition.
(I know that vale is a type of depression)
'virginia starts to languish and experience' is the wordplay.
'virginia' becomes 'va' (US state abbreviation).
'starts to' indicates taking the first letters.
'and' is a charade indicator (letters next to each other).
'experience' becomes 'e' (this might be a standard abbreviation I've not previously seen).
The first letter of 'languish' is 'l'.
'va'+'l'+'e'='VALE'
Can you help me to learn more?
(Other definitions for vale that I've seen before include "Valley" , "Glen; goodbye!" , "'''Sweet ... of Avoca, how calm could I rest'' (Moore) (4)'" , "Trough between ridges" , "Maida -, N. London area; farewell (archaic)" .)