Virtue of Patricia, exceptional niece (8)
I believe the answer is:
patience
'virtue' is the definition.
(I have seen 'The virtue' mean 'patience' so perhaps 'virtue' could also mean 'patience')
'patricia exceptional niece' is the wordplay.
'patricia' becomes 'pat' (I can't justify this - if you can you should give a lot more credence to this answer).
'exceptional' is an anagram indicator (an unusual or exceptional ordering of the letters).
'niece' with letters rearranged gives 'ience'.
'pat'+'ience'='PATIENCE'
'of' is the link.
Can you help me to learn more?
(Other definitions for patience that I've seen before include "Gilbertian dairymaid" , "G & S' alternative for "Bunthorne''s Bride"" , "Composure" , "Calm endurance as in card game for one" , "Waiting without complaint" .)