Waste from fruit and produce picked up (5)
I believe the answer is:
cores
'waste from fruit' is the definition.
(eg apple cores)
'produce picked up' is the wordplay.
'produce' becomes 'cause' (produce can mean to cause or create).
'picked up' shows a homophone (sound like).
'cause' sounds like 'CORES'.
'and' acts as a link.
(Other definitions for cores that I've seen before include "The centres of objects" , "Hearts" , "Central parts" .)