Wax lyrical in this way visiting east Tyneside region (7)
I believe the answer is:
enthuse
'wax lyrical' is the definition.
(both can mean to speak enthusiastically)
'in this way visiting east tyneside region' is the wordplay.
'in this way' becomes 'thus' (synonyms).
'visiting' indicates putting letters inside.
'east tyneside region' becomes 'ene' (I can't justify this - if you can you should give a lot more credence to this answer).
'thus' inserted inside 'ene' is 'ENTHUSE'.
Can you help me to learn more?
(Other definitions for enthuse that I've seen before include "Cheer" , "Show intense approval" , "Express keen interest" , "Show eager interest and liking" , "Gush in praise" .)