Way cool cadenza regularly uplifts fanatics (7)
I believe the answer is:
zealots
'fanatics' is the definition.
(I've seen this before)
'way cool cadenza regularly uplifts' is the wordplay.
'way' becomes 'st' (abbreviation for street).
'regularly' indicates alternate letters (regularly take one letter, leave next etc.).
'uplifts' shows that the letters should be reversed in order.
'cool'+'cadenza'='coolcadenza'
The alternate letters of 'coolcadenza' are 'olaez'.
'st'+'olaez'='stolaez'
'stolaez' reversed gives 'ZEALOTS'.
(Other definitions for zealots that I've seen before include "Extremists" , "Extreme enthusiasts" , "Fanatics" , "Gung-ho types" , "Partisans" .)