Ways of heading off depression before the Sabbath (6)
I believe the answer is:
alleys
'ways' is the definition.
(as in alleyways)
'heading off depression before the sabbath' is the wordplay.
'heading off' means to remove the first letter.
'depression' becomes 'valley' (depression in the ground).
'before' is a charade indicator (letters next to each other).
'the sabbath' becomes 's'.
'valley' with its first letter taken off is 'alley'.
'alley'+'s'='ALLEYS'
'of' acts as a link.
(Other definitions for alleys that I've seen before include "Back lanes" , "Narrow passageways" , "Narrow passages between streets" , "Narrow passages between buildings - some cats frequent them" , "Laneways" .)