We get tough with a horse opera (7)
I believe the answer is:
western
'a horse opera' is the definition.
('Western' can be a synonym of 'horse opera')
'we get tough' is the wordplay.
'get tough' becomes 'stern' (I can't justify this - if you can you should give a lot more credence to this answer).
'we'+'stern'='WESTERN'
'with' is the link.
Can you help me to learn more?
(Other definitions for western that I've seen before include "Cowboys and Indians movie" , "Spaghetti film?" , "The Occident" , "American film" , "Type of film or music" .)