Weary of accommodating doctor's tone (6)
I believe the answer is:
timbre
'tone' is the definition.
(I know that tone can be written as timbre)
'weary of accommodating doctor's' is the wordplay.
I cannot really understand how this works, but
'doctor' could be 'mb' (Bachelor of Medicine) and 'mb' is found within the answer.
'weary' could be 'tire' (synonyms) and 'tire' is found within the remaining letters.
This accounts for all the letters.
This may be the basis of the clue (or it may be nonsense).
Can you help me to learn more?
(Other definitions for timbre that I've seen before include "Quality of voice, sounds wooden" , "The distinctive property of a voice" , "Tone-colour" , "The quality of the speaking voice" , "Ring" .)