What could make a Rev. intone in worship? (10)
I believe the answer is:
veneration
'worship?' is the definition.
(I know that veneration is a type of worship)
'what could make a rev intone' is the wordplay.
'what could make' indicates anagramming the letters.
'a'+'rev'+'intone'='arevintone'
'arevintone' is an anagram of 'VENERATION'.
'in' is the link.
(Other definitions for veneration that I've seen before include "Great respect" , "worship" .)