What may suggest setter's straitened circumstances? (5,6)
I believe the answer is:
queer street
'what may suggest' is the definition.
I can't judge whether this defines the answer.
'setter's straitened circumstances?' is the wordplay.
I cannot quite see how this works, but
an anagram of 'setter' is 'street' which is present in the answer.
The remaining letters 'queer' is a valid word which might be clued in a way I don't see.
This explanation may well be incorrect...
(Other definitions for queer street that I've seen before include "Supposed residences of people in debt" , "The Red" , "in financial difficulties - with 7d" , "Bankrupts' road" .)