What to scream when depressed by Mr Rude's rubbish (4,6)
I believe the answer is:
blue murder
'what to scream' is the definition.
I don't know anything about this answer so I can't judge whether this works.
'depressed by mr rude's rubbish' is the wordplay.
'depressed' becomes 'blue' (I've seen this before).
'by' says to put letters next to each other.
'rubbish' indicates an anagram (a poor quality or rubbish spelling of the letters).
'mr'+'rude'='mrrude'
'mrrude' with letters rearranged gives 'murder'.
'blue'+'murder'='BLUE MURDER'
'when' acts as a link.
Can you help me to learn more?
(Other definitions for blue murder that I've seen before include "Terrible commotion?" , "Great outcry - horrible din" , "racket" .)