What's dropped from hand, and the result (5)
I believe the answer is:
leave
'result' is the definition.
(I know that result can be written as leave)
'what's dropped from hand and' is the wordplay.
'what's dropped from' suggests deleting specific letters.
'hand' becomes 'leave with' (leaving with is a kind of handing).
'and' becomes 'with'.
'leavewith' with 'with' taken away is 'LEAVE'.
'the' acts as a link.
(Other definitions for leave that I've seen before include "consent" , "Desert" , "Don't take - time off" , "Brexit's aim" , "Go away on holiday" .)