Wheels secured by new tool men pick up in race (5,5,5)
I believe the answer is:
monte carlo rally
'race' is the definition.
(annual motorsport event)
'wheels secured by new tool men pick up' is the wordplay.
I cannot quite see how this works, but
'wheels' could be 'car' (car wheel is a kind of wheel) and 'car' is found within the answer.
'new' could be 'n' (common abbreviation eg NT for New Testament) and 'n' is found in the answer.
'men' could be 'or' (military abbreviation for Other Ranks) and 'or' is located in the answer.
This explanation may well be incorrect...
'in' is the link.
(Other definitions for monte carlo rally that I've seen before include "Driving competition" , "famous motor-race" , "European car race" , "driving test" .)