When out of whiskey wild-eyed crazy gave in (7)
I believe the answer is:
yielded
'gave in' is the definition.
('yield' can be a synonym of 'give in')
'when out of whiskey wild-eyed crazy' is the wordplay.
'when out of' suggests deleting specific letters.
'whiskey' becomes 'w' (alpha bravo charlie delta ...).
'crazy' indicates an anagram.
'wild'+'eyed'='wildeyed'
'wildeyed' with 'w' removed is 'ildeyed'.
'ildeyed' anagrammed gives 'YIELDED'.
(Other definitions for yielded that I've seen before include "was paid" , "Gave ground" , "succumbed" , "abandoned" , "Gave way under pressure" .)