Wife brought into A&E? A little overwhelming (7)
I believe the answer is:
awesome
'overwhelming' is the definition.
(awesome can mean awe-inspiring)
'wife brought into ae? a little' is the wordplay.
'wife' becomes 'w'.
'brought into' is an insertion indicator.
'a little' becomes 'some' (I've seen this before).
'w' going inside 'ae' is 'awe'.
'awe'+'some'='AWESOME'
(Other definitions for awesome that I've seen before include "Inspiring admiration - wonderful!" , "Dreadful; amazing" , "Terrifying" , "Exceptionally good" , "Amazing (sl.)" .)