Wild party outside home brings depression (6)
I believe the answer is:
ravine
'depression' is the definition.
(ravine is a kind of depression)
'wild party outside home' is the wordplay.
'wild party' becomes 'rave' (I've seen this before).
'outside' means one lot of letters goes inside another.
'home' becomes 'in' ('he's home' can mean 'he's in').
'rave' enclosing 'in' is 'RAVINE'.
'brings' acts as a link.
(Other definitions for ravine that I've seen before include "Defile" , "Narrow, steep-sided valley" , "Type of gorge" , "Deep narrow valley" , "Vainer in narrow gorge" .)