Wilder perhaps in Penge neighbourhood (4)
I believe the answer is:
gene
'wilder' is the definition.
(gene wilder)
'in penge neighbourhood' is the wordplay.
'in' indicates the answer is hidden within the clue.
'GENE' is hidden in the letters of 'penge neighbourhood'.
'perhaps' acts as a link.
(Other definitions for gene that I've seen before include "and 16 Down: Rockabilly singer" , "Embarrassment" , "DNA unit" , "affects someone's make-up" , "Element of heredity" .)