Window sounds a nuisance (4)
I believe the answer is:
pane
'window' is the definition.
(thesaurus)
'sounds a nuisance' is the wordplay.
'sounds' shows a homophone (sound like).
'a nuisance' becomes 'pain' ('pain' can be a synonym of 'nuisance').
'pain' sounds like 'PANE'.
(Other definitions for pane that I've seen before include "Single sheet of glass in a window" , "Piece of glass in window" , "Panel of glass" .)