Wine brewed nearest us (9)
I believe the answer is:
sauternes
'wine' is the definition.
(Sauternes is an example)
'brewed nearest us' is the wordplay.
'brewed' indicates anagramming the letters.
'nearest'+'us'='nearestus'
'nearestus' with letters rearranged gives 'SAUTERNES'.
(Other definitions for sauternes that I've seen before include "A sweet Bordeaux" , "Sweet white wine" , "Sweet French wine" .)