Wine from the East Indies? (4)
I believe the answer is:
asti
'wine' is the definition.
(Italian wine)
'from the east indies?' is the wordplay.
'from' says the answer is hidden in the clue.
'ASTI' is hidden within 'east indies'.
(Other definitions for asti that I've seen before include "Piedmontese white wine" , "town in Italy" , "Italian 'sparkler'" , "White wine named after a town in Piedmont" , "Sparkling wine named after an Italian Piedmont town" .)