Wine initially gives me intoxication and sight issues (8)
I believe the answer is:
astigmia
'sight issues' is the definition.
(type of eye problem)
'wine initially gives me intoxication and' is the wordplay.
'wine' becomes 'asti' (I've seen this before).
'initially' suggests taking the first letters.
The first letters of 'gives me intoxication and' is 'gmia'.
'asti'+'gmia'='ASTIGMIA'
I've seen this clue in The Guardian.
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