Wine man holding firm (5)
I believe the answer is:
macon
'wine' is the definition.
(macon is a kind of wine)
'man holding firm' is the wordplay.
'holding' indicates putting letters inside.
'firm' becomes 'co' (a firm is a company).
'man' placed around 'co' is 'MACON'.
(Other definitions for macon that I've seen before include "French wine region" , "Drink" , "Dry white Burgundy wine" , "Variety of Burgundy" , "red" .)