Winemaker’s very esoteric about it, ultimately (7)
I believe the answer is:
vintner
'winemaker's' is the definition.
(synonyms)
'very esoteric about it ultimately' is the wordplay.
'very' becomes 'v' (common abbreviation).
'esoteric' becomes 'inner' (I've seen this before).
'about' indicates putting letters inside.
'ultimately' says to take the final letters.
The last letter of 'it' is 't'.
'inner' going around 't' is 'intner'.
'v'+'intner'='VINTNER'
(Other definitions for vintner that I've seen before include "Wine producer" , "Wine seller" , "one in red and white?" , "A wine-merchant" , "Wine merchant" .)