Wipe out cholera, seemingly contained within (5)
I believe the answer is:
erase
'wipe out' is the definition.
('erase' can be a synonym of 'wipe out')
'cholera seemingly contained within' is the wordplay.
'within' indicates the answer is hidden within the clue.
'ERASE' is hidden in the letters of 'cholera seemingly contained'.
(Other definitions for erase that I've seen before include "Delete" , "Remove permanently" , "To remove all trace" , "score" , "Kill" .)