Wise eccentric in panties (7)
I believe the answer is:
sapient
'wise' is the definition.
(similar in meaning)
'eccentric in panties' is the wordplay.
'panties' can be anagrammed to 'SAPIENT'.
Though, I am unsure how the anagram is indicated.
Can you help me to learn more?
(Other definitions for sapient that I've seen before include "Literary word for wise" , "Panties (anag)" , "Canny" , "Snipe at (anag.)" , "of great wisdom" .)