With me, our son confused giant (8)
I believe the answer is:
enormous
'giant' is the definition.
(I've seen this before)
'with me our son confused' is the wordplay.
'with' means one lot of letters go next to another.
'confused' is an anagram indicator.
'me'+'our'='meour'
'meour'+'son' is 'meourson'.
'meourson' with letters rearranged gives 'ENORMOUS'.
(Other definitions for enormous that I've seen before include "'Huge, gigantic (8)'" , "Massive" , "Tremendous, gigantic" , "Extraordinarily large" , "Mammoth" .)