With some medicine bottles, seek water (5)
I believe the answer is:
dowse
'seek water' is the definition.
(dowsing is a supposed method of looking for water)
'with some medicine bottles' is the wordplay.
'with' becomes 'w' (abbreviation).
'some medicine' becomes 'dose' (dose is a kind of medicine).
'bottles' means one lot of letters goes inside another (bottle can mean to contain).
'w' going into 'dose' is 'DOWSE'.
(Other definitions for dowse that I've seen before include "try to find water" , "put fire out" , "Use rods to find water" , "Search for water using hazel twig" , "Search for underground water using rod" .)