With target organised, allowing no escape (10)
I believe the answer is:
watertight
'allowing no escape' is the definition.
'with target organised' is the wordplay.
'organised' indicates anagramming the letters.
'with'+'target'='withtarget'
'withtarget' with letters rearranged gives 'WATERTIGHT'.
(Other definitions for watertight that I've seen before include "Unassailable" , "Impregnable" , "Without loopholes" , "Proof against leaking" , "seaworthy" .)