Withdraw and give up again? (6)
I believe the answer is:
recede
I believe this clue is a double definition.
'withdraw' is the first definition.
('recede' can be a synonym of 'withdraw')
'give up again?' is the second definition.
('cede' can be a synonym for 'give up' so perhaps 'recede' is OK for 'give up again')
'and' acts as a link.
(Other definitions for recede that I've seen before include "Decree (anag) - ebb" , "Go backwards" , "Start balding" , "Go back, ebb" , "Become more distant" .)