Without a care to take medicine, ecstasy or liqueur (5)
I believe the answer is:
creme
'liqueur' is the definition.
I don't know anything about this answer so I cannot tell whether it can be defined by this definition.
'without a care to take medicine ecstasy' is the wordplay.
'without' indicates named letters should be taken away.
'to take' says to put letters next to each other.
'medicine ecstasy' becomes 'me' (this could be a standard abbreviation of which I'm unaware).
'care' with 'a' taken away is 'cre'.
'cre'+'me'='CREME'
'or' is the link.
Can you help me to learn more?
(Another definition for creme that I've seen is " Cream to the French".)