Without a doubt, transfusions with blood regularly administered (2,3,4,2,4)
I believe the answer is:
no ifs ands or buts
'without a doubt' is the definition.
'transfusions with blood regularly administered' is the wordplay.
'with' says to put letters next to each other.
'regularly' indicates alternate letters (regularly take one letter, leave next etc.).
'administered' indicates an anagram (administering the letters).
The alternating letters of 'blood' are 'bod'.
'transfusions' put after 'bod' is 'bodtransfusions'.
'bodtransfusions' with letters rearranged gives 'NO IFS ANDS OR BUTS'.
I've seen this clue in The Guardian.
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